Lactic acid - main properties

1, moisture: with water, ethanol, glycerol miscible, acidic aqueous solution, PKa = 2.5. Insoluble in calcium lactate, carbon disulfide and petroleum ether. Heating under normal pressure, concentrated to 50%, the part becomes the lactic anhydride, product often contains 10% to 15% of the milk anhydride, as having a hydroxyl group and a carboxyl group, under certain conditions, the esterification reaction can occur, the product has three kind.

2 toxicity: rat oral LD50 for 3.73g/kg weight; ADI Unlimited regulations. Lactic acid has three isomers: DL-type, D-type and L-type. The rats were divided into three groups, each dosage dose of 1.7g/kg body weight of DL-type, D-type and potassium lactate, oral anatomy detected three hours later, DL-lactic acid can increase the liver glycogen , 40% to 95% within 3h absorption and transformation; D-and L-lactic acid in the blood lactate increased, there is excreted in the urine.

3, Biology: lactate dehydrogenase in the fermentation process pyruvate is converted to Calcium lactate. In general, the lactic acid metabolism and movement is generated continuously, but its concentration is generally not rise. Only in lactate production speed up the process, lactic acid can not be transported in a timely manner when the concentration will increase. Acid transport speed by a series of factors, including monocarboxylic transporter, lactate dehydrogenase concentration and isomeric forms, tissue oxidation. Generally the concentration of lactate in the blood is not in movement 1-2mmol / L, in the strong movement can rise to 20mmol / L.