Lactococcus nitrile collocation method

Lactonitrile law: Lactonitrile method is to acetaldehyde and hydrogen cyanide cold milk continuously fed to the reactor to generate a nitrile (or directly with the milk as raw material nitrile), with a pump into the milk nitrile hydrolysis reactor, into sulfuric acid and Zinc lactate, the milk nitrilase crude lactic acid. And then give it away crude lactic acid esterification reactor, adding ethanol esterification, distillation, concentration, lactic acid decomposition was fine. American Sterling Chemical Company and Japan Musashino Chemical companies are adopting this synthesis of lactic acid.
Acrylonitrile law: acrylonitrile and acrylonitrile method is hydrolyzed in sulfuric acid fed to the reactor, and then hydrolysis reactor anyone to esterification reaction with methanol; then after separation of the hydrogen sulfate, the crude ester distillation column , the bottom was fine ester; then refined into a second distillation column ester, thermal decomposition, bottom too thin ferrous lactate, concentrated by vacuum to obtain the product.
Propionic acid method: method propionic acid as raw materials, through chlorination, hydrolysis of the crude lactic acid; re-esterification, distillation, hydrolysis products. This method is more expensive raw materials, only a few companies such as Japan's road contest manufacturers to adopt. Reaction is as follows: CH3CH2COOH Cl2 one → CH3CHClCOOH NaOH-→ CH3CH (OH) COOH NaCl